UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q5VVX9 (Uniprot)	UBE2U_HUMAN	UBE2U	Ubiquitin-conjugating enzyme E2 U	human	No

Protein Function

Uniprot: Catalyzes the covalent attachment of ubiquitin to other proteins.

MoonDB Dissimilar Functions

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0009056	catabolic process	125	GO:0009059	macromolecule biosynthetic process	270, 384	6.37e-04	1.88e-40

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MoonDB Network Modules

Biological Processes

Showing 1 to 10 of 26 entries

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Module ID (MoonGO)	GO ID (BP)	GO Name
125	GO:0044248	cellular catabolic process
125	GO:0016567	protein ubiquitination
125	GO:0060255	regulation of macromolecule metabolic process
164	GO:0044267	cellular protein metabolic process
164	GO:0060255	regulation of macromolecule metabolic process
164	GO:0007165	signal transduction
270	GO:0034645	cellular macromolecule biosynthetic process
270	GO:0010467	gene expression
270	GO:0090304	nucleic acid metabolic process
270	GO:0032446	protein modification by small protein conjugation

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Cellular Components

Showing 1 to 10 of 17 entries

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Module ID (MoonGO)	GO ID (CC)	GO Name
18	GO:0005829	cytosol
18	GO:0070062	extracellular exosome
125	GO:0005829	cytosol
125	GO:0005634	nucleus
270	GO:0005829	cytosol
270	GO:0070013	intracellular organelle lumen
270	GO:0005634	nucleus
289	GO:0005634	nucleus
375	GO:0005829	cytosol
375	GO:0005634	nucleus

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Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0000209	protein polyubiquitination	IBA
GO:0006281	DNA repair	IBA
GO:0016574	histone ubiquitination	IBA
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA

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Cellular Components

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0000790	nuclear chromatin	IBA
GO:0005737	cytoplasm	IBA
GO:0033503	HULC complex	IBA

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Dissimilar Cellular Components (PrOnto)

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GO ID 1	Component 1	GO ID 2	Component 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0000790	nuclear chromatin	GO:0005737	cytoplasm	4.55e-08	5.17e-23

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All Protein Interactions

Showing 1 to 10 of 69 entries

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Interactor	Also a MoonDB EMF protein
APC11_HUMAN	No
BARD1_HUMAN	No
BFAR_HUMAN	No
CAPS2_HUMAN	No
CGRF1_HUMAN	No
DTX1_HUMAN	No
DZIP3_HUMAN	No
GOGA2_HUMAN	Yes: Q08379 (MoonDB)
HOIL1_HUMAN	No
KAT6A_HUMAN	No

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Publications Associated

Showing 1 to 3 of 3 entries

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PMID	Article Title
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
16710414	The DNA sequence and biological annotation of human chromosome 1.
22496338	A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 8 of 8 entries

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Domain Name	Domain ID	Source
SSF54495	SSF54495	SUPFAM
UBCc	cd00195	CDD
UBIQUITIN_CONJUGAT_1	PS00183	PROSITE
UBIQUITIN_CONJUGAT_2	PS50127	PROSITE
UBQ-conjugat_E2	IPR000608	InterPro
UBQ-conjugating_AS	IPR023313	InterPro
UBQ-conjugating_enzyme/RWD	IPR016135	InterPro
UQ_con	PF00179	Pfam

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