Protein: P29055 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
P29055 (Uniprot)	TF2B_YEAST	SUA7	Transcription initiation factor IIB	yeast	No

Protein Function

Uniprot: General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.

MoonDB Dissimilar Functions

Showing 1 to 10 of 12 entries

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0006139	nucleobase-containing compound metabolic process	1059, 1078	GO:0006811	ion transport	1226	1.46e-19	8.47e-83
GO:0006351	transcription, DNA-templated	1378	GO:0015833	peptide transport	941	7.52e-08	6.04e-70
GO:0006725	cellular aromatic compound metabolic process	1220	GO:0006811	ion transport	1226	1.93e-19	6.20e-85
GO:0006811	ion transport	1226	GO:0034641	cellular nitrogen compound metabolic process	1337	4.44e-27	1.76e-86
GO:0006811	ion transport	1226	GO:0006351	transcription, DNA-templated	1378	2.52e-16	2.35e-48
GO:0009059	macromolecule biosynthetic process	1139, 1258	GO:0015833	peptide transport	941	5.69e-13	2.89e-52
GO:0009059	macromolecule biosynthetic process	1139, 1258	GO:0006811	ion transport	1226	2.67e-40	7.66e-50
GO:0009987	cellular process	1066	GO:0006811	ion transport	1226	8.14e-56	7.39e-38
GO:0043170	macromolecule metabolic process	1083, 1132, 1219	GO:0015833	peptide transport	941	3.85e-11	1.47e-03
GO:0043170	macromolecule metabolic process	1083, 1132, 1219	GO:0006811	ion transport	1226	7.11e-80	2.62e-84

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MoonDB Network Modules

Biological Processes

Showing 1 to 10 of 37 entries

Search:

Module ID (MoonGO)	GO ID (BP)	GO Name
915	GO:0016070	RNA metabolic process
915	GO:0010467	gene expression
915	GO:0060255	regulation of macromolecule metabolic process
941	GO:0015031	protein transport
1014	GO:0034622	cellular macromolecular complex assembly
1014	GO:0006139	nucleobase-containing compound metabolic process
1017	GO:0034314	Arp2/3 complex-mediated actin nucleation
1059	GO:0090304	nucleic acid metabolic process
1064	GO:0016070	RNA metabolic process
1064	GO:0044271	cellular nitrogen compound biosynthetic process

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Cellular Components

Showing 1 to 10 of 22 entries

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Module ID (MoonGO)	GO ID (CC)	GO Name
915	GO:0005634	nucleus
941	GO:0012505	endomembrane system
984	GO:0012505	endomembrane system
1014	GO:0005634	nucleus
1017	GO:0030479	actin cortical patch
1059	GO:0005634	nucleus
1064	GO:0005634	nucleus
1066	GO:0044454	nuclear chromosome part
1078	GO:0005634	nucleus
1083	GO:0005634	nucleus

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Protein GO Annotations

Biological Processes

Showing 1 to 5 of 5 entries

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0001113	transcriptional open complex formation at RNA polymerase II promoter	IMP
GO:0001174	transcriptional start site selection at RNA polymerase II promoter	IMP
GO:0006355	regulation of transcription, DNA-templated	IEA
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	IMP
GO:2000679	positive regulation of transcription regulatory region DNA binding	IDA

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Cellular Components

Showing 1 to 2 of 2 entries

Search:

GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005634	nucleus	IDA
GO:0097550	transcriptional preinitiation complex	IDA

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 101 entries

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Interactor	Also a MoonDB EMF protein
ADD37_YEAST	No
ALDH5_YEAST	No
ARL3_YEAST	No
ARP3_YEAST	No
ATP14_YEAST	Yes: Q12349 (MoonDB)
ATPN_YEAST	No
ATX2_YEAST	No
BCD1_YEAST	No
BRE1_YEAST	No
BUD3_YEAST	No

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Publications Associated

Showing 1 to 5 of 5 entries

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PMID	Article Title
1547497	The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo.
9169875	The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
14562106	Global analysis of protein expression in yeast.
17322287	Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
24374639	The reference genome sequence of Saccharomyces cerevisiae: Then and now.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 10 of 16 entries

Search:

Domain Name	Domain ID	Source
CYCLIN	SM00385	SMART
CYCLIN	cd00043	CDD
Cyclin-like	IPR013763	InterPro
Cyclin-like_sf	IPR036915	InterPro
PTHR11618	PTHR11618	PANTHER
S26707	S26707	PIR
SSF47954	SSF47954	SUPFAM
TF_Zn_Ribbon	PF08271	Pfam
TFIIB	IPR000812	InterPro
TFIIB	PF00382	Pfam

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