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A Database of Extreme Multifunctional and Moonlighting Proteins
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Protein: P98175
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
P98175 (Uniprot)
RBM10_HUMAN
RBM10
RNA-binding protein 10
human
No
Protein Function
Uniprot:
May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins (PubMed:28431233).
MoonDB Dissimilar Functions
Showing 1 to 1 of 1 entries
Search:
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0006396
RNA processing
426
GO:0036211
protein modification process
440
,
555
5.60e-03
3.14e-16
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MoonDB Network Modules
Biological Processes
Showing 1 to 10 of 36 entries
Search:
Module ID
(MoonGO)
GO ID (BP)
GO Name
31
GO:0034645
cellular macromolecule biosynthetic process
31
GO:0044271
cellular nitrogen compound biosynthetic process
31
GO:0090304
nucleic acid metabolic process
31
GO:0010468
regulation of gene expression
167
GO:0016070
RNA metabolic process
167
GO:0010467
gene expression
167
GO:0060255
regulation of macromolecule metabolic process
191
GO:0006355
regulation of transcription, DNA-templated
353
GO:0000398
mRNA splicing, via spliceosome
426
GO:0008380
RNA splicing
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Cellular Components
Showing 1 to 10 of 14 entries
Search:
Module ID
(MoonGO)
GO ID (CC)
GO Name
31
GO:0005634
nucleus
167
GO:0005654
nucleoplasm
191
GO:0031981
nuclear lumen
353
GO:0005654
nucleoplasm
426
GO:0005654
nucleoplasm
440
GO:0005829
cytosol
440
GO:0005634
nucleus
440
GO:0005886
plasma membrane
440
GO:0031982
vesicle
458
GO:0005634
nucleus
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Protein GO Annotations
Biological Processes
Showing 1 to 5 of 5 entries
Search:
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0000381
regulation of alternative mRNA splicing, via spliceosome
IEA
GO:0006397
mRNA processing
IEA
GO:0008150
biological_process
ND
GO:0008380
RNA splicing
IEA
GO:0042981
regulation of apoptotic process
IEA
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Cellular Components
Showing 1 to 2 of 2 entries
Search:
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005634
nucleus
IDA
GO:0016607
nuclear speck
IDA
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Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Showing 1 to 10 of 42 entries
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Interactor
Also a MoonDB EMF protein
AES_HUMAN
Yes:
Q08117 (MoonDB)
ATN1_HUMAN
No
BAHD1_HUMAN
No
BEND7_HUMAN
No
CCAR1_HUMAN
No
CEP70_HUMAN
No
CPSF7_HUMAN
No
CSK21_HUMAN
Yes:
P68400 (MoonDB)
DDX17_HUMAN
No
DDX5_HUMAN
No
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Publications Associated
Showing 1 to 10 of 25 entries
Search:
PMID
Article Title
8590280
Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.
8808293
A novel gene, DXS8237E, lies within 20 kb upstream of UBE1 in Xp11.23 and has a different X inactivation status.
12176931
Large-scale proteomic analysis of the human spliceosome.
14702039
Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15772651
The DNA sequence of the human X chromosome.
16959974
The consensus coding sequences of human breast and colorectal cancers.
17081983
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
17525332
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
17707232
A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.
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OMIM Diseases Associated
Showing 1 to 1 of 1 entries
Search:
OMIM ID
Disease Name
311900
TARP syndrome
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Protein Domains Associated
Showing 1 to 10 of 25 entries
Search:
Domain Name
Domain ID
Source
G-patch
PF01585
Pfam
G_PATCH
PS50174
PROSITE
G_patch
SM00443
SMART
G_patch_dom
IPR000467
InterPro
OCRE_RBM10
cd16167
CDD
PTHR13948:SF4
PTHR13948:SF4
PANTHER
RBD_domain_sf
IPR035979
InterPro
RBM10
IPR033095
InterPro
RBM10_OCRE
IPR035618
InterPro
RBM10_RRM2
IPR034992
InterPro
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